Ki-67 immunostaining in node-negative stage I/II breast carcinoma. Significant correlation with prognosis
نویسندگان
چکیده
منابع مشابه
Lymph node metastases displaying lower Ki-67 immunostaining activity than the primary breast cancer.
UNLABELLED The aim of the study was to verify by Ki-67 immunostaining if any difference exists in the cell proliferating fraction between primary breast tumors (PTs) and matching positive axillary lymph nodes (ALNs). PATIENTS AND METHODS Immunohistochemistry with the monoclonal antibody against Ki-67 was performed in 160 node-positive breast carcinomas and in their respective lymph node metas...
متن کاملClaudin 4 expression in triple-negative breast cancer: correlation with androgen receptors and Ki-67 expression.
Breast cancer is the most common malignancy in women and the leading cause of cancer mortality worldwide. Triple-negative breast cancer (TNBC) is an important phenotype of breast cancer that accounts for a relatively small number of breast cancer cases but still represent a focus of increasing interest at the clinical, biological, and epidemiological level. Claudins are the major component of t...
متن کاملPrognostic value of Ki-67 compared to S-phase fraction in axillary node-negative breast cancer.
The primary purpose of this study was to evaluate the prognostic significance of Ki-67, a cell proliferation-associated antigen, in a large group (n = 674) of axillary node-negative breast cancer cases with long-term follow-up and to correlate Ki-67 antigen expression with S-phase fraction. Ki-67 immunostaining was assessed both semiquantitatively and quantitatively. The statistical analysis fo...
متن کاملImaging, Diagnosis, Prognosis Performanceof p16/Ki-67 Immunostaining toDetectCervical Cancer Precursors in a Colposcopy Referral Population
Purpose:Cytology-based screening has limited sensitivity to detect prevalent cervical precancers. Human papilloma virus (HPV) DNA testing is highly sensitive and provides a high, long-term reassurance of low risk of cervical cancer. However, the specificity of HPV DNA testing is limited, requiring additional, more disease-specific markers for efficient screening approaches. Experimental Design:...
متن کاملUtility of Ki-67 (MIB-1) Immunostaining in Cervical Biopsies
Nearly every pathologist that practices in a community hospital setting struggles with the accurate and reproducible identification of HPV effect and dysplasia in the female genital tract, and recognizes the fact that in certain situations these conditions can be very difficult to distinguish from reactive changes. Last month in the ProPath "Focus on Immunohistochemistry", we reviewed the poten...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer
سال: 1991
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19910801)68:3<549::aid-cncr2820680318>3.0.co;2-j